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FE65 Binds Teashirt, Inhibiting Expression of the Primate-Specific Caspase-4
The Alzheimer disease (AD) amyloid protein precursor (APP) can bind the FE65 adaptor protein and this complex can regulate gene expression. We carried out yeast two-hybrid studies with a PTB domain of FE65, focusing on those genes that might be involved in nuclear signaling, and identified and valid...
Autores principales: | Kajiwara, Yuji, Akram, Afia, Katsel, Pavel, Haroutunian, Vahram, Schmeidler, James, Beecham, Gary, Haines, Jonathan L., Pericak-Vance, Margaret A., Buxbaum, Joseph D. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660419/ https://www.ncbi.nlm.nih.gov/pubmed/19343227 http://dx.doi.org/10.1371/journal.pone.0005071 |
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