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Impaired Mitochondrial Function and Insulin Resistance of Skeletal Muscle in Mitochondrial Diabetes

OBJECTIVE: Impaired muscular mitochondrial function is related to common insulin resistance in type 2 diabetes. Mitochondrial diseases frequently lead to diabetes, which is mostly attributed to defective β-cell mitochondria and secretion. RESEARCH DESIGN AND METHODS: We assessed muscular mitochondri...

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Detalles Bibliográficos
Autores principales: Szendroedi, Julia, Schmid, Albrecht Ingo, Meyerspeer, Martin, Cervin, Camilla, Kacerovsky, Michaela, Smekal, Gerhard, Gräser-Lang, Sabine, Groop, Leif, Roden, Michael
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660467/
https://www.ncbi.nlm.nih.gov/pubmed/19131470
http://dx.doi.org/10.2337/dc08-2078