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In Situ-Targeting of Dendritic Cells with Donor-Derived Apoptotic Cells Restrains Indirect Allorecognition and Ameliorates Allograft Vasculopathy

Chronic allograft vasculopathy (CAV) is an atheromatous-like lesion that affects vessels of transplanted organs. It is a component of chronic rejection that conventional immuno-suppression fails to prevent, and is a major cause of graft loss. Indirect allo-recognition through T cells and allo-Abs ar...

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Detalles Bibliográficos
Autores principales: Wang, Zhiliang, Shufesky, William J., Montecalvo, Angela, Divito, Sherrie J., Larregina, Adriana T., Morelli, Adrian E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660580/
https://www.ncbi.nlm.nih.gov/pubmed/19333400
http://dx.doi.org/10.1371/journal.pone.0004940