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In Situ-Targeting of Dendritic Cells with Donor-Derived Apoptotic Cells Restrains Indirect Allorecognition and Ameliorates Allograft Vasculopathy
Chronic allograft vasculopathy (CAV) is an atheromatous-like lesion that affects vessels of transplanted organs. It is a component of chronic rejection that conventional immuno-suppression fails to prevent, and is a major cause of graft loss. Indirect allo-recognition through T cells and allo-Abs ar...
Autores principales: | Wang, Zhiliang, Shufesky, William J., Montecalvo, Angela, Divito, Sherrie J., Larregina, Adriana T., Morelli, Adrian E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660580/ https://www.ncbi.nlm.nih.gov/pubmed/19333400 http://dx.doi.org/10.1371/journal.pone.0004940 |
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