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Effect of Nanoparticles on Protein Folding and Fibrillogenesis

The large surface area and small size of nanoparticles provide properties and applications that are distinct from those of bulk materials. The ability of nanoparticles to influence protein folding and aggregation is interesting, not only because of the potential beneficial applications, but also the...

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Detalles Bibliográficos
Autores principales: Fei, Li, Perrett, Sarah
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660666/
https://www.ncbi.nlm.nih.gov/pubmed/19333426
http://dx.doi.org/10.3390/ijms10020646
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author Fei, Li
Perrett, Sarah
author_facet Fei, Li
Perrett, Sarah
author_sort Fei, Li
collection PubMed
description The large surface area and small size of nanoparticles provide properties and applications that are distinct from those of bulk materials. The ability of nanoparticles to influence protein folding and aggregation is interesting, not only because of the potential beneficial applications, but also the potential risks to human health and the environment. This makes it essential that we understand the effect of nanoparticles on fundamental biological process, like protein folding. Here, we review studies that have examined the effect of nanoparticles on protein folding and aggregation, providing insight both into the mechanisms of these processes and how they may be controlled.
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spelling pubmed-26606662009-03-30 Effect of Nanoparticles on Protein Folding and Fibrillogenesis Fei, Li Perrett, Sarah Int J Mol Sci Review The large surface area and small size of nanoparticles provide properties and applications that are distinct from those of bulk materials. The ability of nanoparticles to influence protein folding and aggregation is interesting, not only because of the potential beneficial applications, but also the potential risks to human health and the environment. This makes it essential that we understand the effect of nanoparticles on fundamental biological process, like protein folding. Here, we review studies that have examined the effect of nanoparticles on protein folding and aggregation, providing insight both into the mechanisms of these processes and how they may be controlled. Molecular Diversity Preservation International (MDPI) 2009-02-20 /pmc/articles/PMC2660666/ /pubmed/19333426 http://dx.doi.org/10.3390/ijms10020646 Text en © 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Fei, Li
Perrett, Sarah
Effect of Nanoparticles on Protein Folding and Fibrillogenesis
title Effect of Nanoparticles on Protein Folding and Fibrillogenesis
title_full Effect of Nanoparticles on Protein Folding and Fibrillogenesis
title_fullStr Effect of Nanoparticles on Protein Folding and Fibrillogenesis
title_full_unstemmed Effect of Nanoparticles on Protein Folding and Fibrillogenesis
title_short Effect of Nanoparticles on Protein Folding and Fibrillogenesis
title_sort effect of nanoparticles on protein folding and fibrillogenesis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660666/
https://www.ncbi.nlm.nih.gov/pubmed/19333426
http://dx.doi.org/10.3390/ijms10020646
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