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Promoter methylation correlates with reduced NDRG2 expression in advanced colon tumour

BACKGROUND: Aberrant DNA methylation of CpG islands of cancer-related genes is among the earliest and most frequent alterations in cancerogenesis and might be of value for either diagnosing cancer or evaluating recurrent disease. This mechanism usually leads to inactivation of tumour-suppressor gene...

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Detalles Bibliográficos
Autores principales:	Piepoli, Ada, Cotugno, Rosa, Merla, Giuseppe, Gentile, Annamaria, Augello, Bartolomeo, Quitadamo, Michele, Merla, Antonio, Panza, Anna, Carella, Massimo, Maglietta, Rosalia, D'Addabbo, Annarita, Ancona, Nicola, Fusilli, Saverio, Perri, Francesco, Andriulli, Angelo
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660908/ https://www.ncbi.nlm.nih.gov/pubmed/19257893 http://dx.doi.org/10.1186/1755-8794-2-11

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