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Elite Suppressor–Derived HIV-1 Envelope Glycoproteins Exhibit Reduced Entry Efficiency and Kinetics

Elite suppressors (ES) are a rare subset of HIV-1–infected individuals who are able to maintain HIV-1 viral loads below the limit of detection by ultra-sensitive clinical assays in the absence of antiretroviral therapy. Mechanism(s) responsible for this elite control are poorly understood but likely...

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Detalles Bibliográficos
Autores principales: Lassen, Kara G., Lobritz, Michael A., Bailey, Justin R., Johnston, Samantha, Nguyen, Sandra, Lee, Benhur, Chou, Tom, Siliciano, Robert F., Markowitz, Martin, Arts, Eric J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661022/
https://www.ncbi.nlm.nih.gov/pubmed/19360131
http://dx.doi.org/10.1371/journal.ppat.1000377