Cargando…
Elite Suppressor–Derived HIV-1 Envelope Glycoproteins Exhibit Reduced Entry Efficiency and Kinetics
Elite suppressors (ES) are a rare subset of HIV-1–infected individuals who are able to maintain HIV-1 viral loads below the limit of detection by ultra-sensitive clinical assays in the absence of antiretroviral therapy. Mechanism(s) responsible for this elite control are poorly understood but likely...
Autores principales: | Lassen, Kara G., Lobritz, Michael A., Bailey, Justin R., Johnston, Samantha, Nguyen, Sandra, Lee, Benhur, Chou, Tom, Siliciano, Robert F., Markowitz, Martin, Arts, Eric J. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661022/ https://www.ncbi.nlm.nih.gov/pubmed/19360131 http://dx.doi.org/10.1371/journal.ppat.1000377 |
Ejemplares similares
-
HIV-1 Entry, Inhibitors, and Resistance
por: Lobritz, Michael A., et al.
Publicado: (2010) -
An entry-competent intermediate state of the HIV-1 envelope glycoproteins
por: Herschhorn, Alon, et al.
Publicado: (2017) -
HIV-1 Envelope Glycoprotein Variable Loops Are Indispensable for Envelope Structural Integrity and Virus Entry
por: Yuan, Tingting, et al.
Publicado: (2013) -
Maintenance of viral suppression in HIV-1–infected HLA-B*57(+) elite suppressors despite CTL escape mutations
por: Bailey, Justin R., et al.
Publicado: (2006) -
HIV-1 Diversity in the Envelope Glycoproteins: Implications for Viral Entry Inhibition
por: Araújo, Leonardo Augusto Luvison, et al.
Publicado: (2013)