Cargando…

Resistance to cisplatin does not affect sensitivity of human ovarian cancer cell lines to mifepristone cytotoxicity

BACKGROUND: The prototypical antiprogestin mifepristone exhibits potent growth inhibition activity towards ovarian cancer cells in vitro and in vivo. The aim of this research was to establish whether mifepristone is capable of inhibiting cell proliferation and inducing apoptotic cell death regardles...

Descripción completa

Detalles Bibliográficos
Autores principales:	Freeburg, Elizabeth M, Goyeneche, Alicia A, Seidel, Erin E, Telleria, Carlos M
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661041/ https://www.ncbi.nlm.nih.gov/pubmed/19222856 http://dx.doi.org/10.1186/1475-2867-9-4

Ejemplares similares

Mifepristone inhibits non-small cell lung carcinoma cellular escape from DNA damaging cisplatin
por: Kapperman, Heather E., et al.
Publicado: (2018)

Mifepristone prevents repopulation of ovarian cancer cells escaping cisplatin-paclitaxel therapy
por: Goyeneche, Alicia A, et al.
Publicado: (2012)

Anticancer effects of mifepristone on human uveal melanoma cells
por: Alvarez, Prisca Bustamante, et al.
Publicado: (2021)

Resistance to cisplatin and paclitaxel does not affect the sensitivity of human ovarian cancer cells to antiprogestin-induced cytotoxicity
por: Gamarra-Luques, Carlos D, et al.
Publicado: (2014)

Long-term primary culture of a clear cell ovarian carcinoma reveals an epithelial–mesenchymal cooperative interaction
por: Goyeneche, Alicia A., et al.
Publicado: (2015)

The metastatic capacity of high-grade serous ovarian cancer cells changes along disease progression: inhibition by mifepristone
por: Ritch, Sabrina J., et al.
Publicado: (2022)

Advanced assessment of migration and invasion of cancer cells in response to mifepristone therapy using double fluorescence cytochemical labeling
por: Ritch, Sabrina J., et al.
Publicado: (2019)

Growth inhibition induced by antiprogestins RU-38486, ORG-31710, and CDB-2914 in ovarian cancer cells involves inhibition of cyclin dependent kinase 2
por: Goyeneche, Alicia A., et al.
Publicado: (2011)

Antiprogestin mifepristone inhibits the growth of cancer cells of reproductive and non-reproductive origin regardless of progesterone receptor expression
por: Tieszen, Chelsea R, et al.
Publicado: (2011)

Synergistic Lethality of Mifepristone and LY294002 in Ovarian Cancer Cells
por: Wempe, Stacy L., et al.
Publicado: (2013)

Mifepristone improves chemo-radiation response in glioblastoma xenografts
por: Llaguno-Munive, Monserrat, et al.
Publicado: (2013)

Cytostasis and morphological changes induced by mifepristone in human metastatic cancer cells involve cytoskeletal filamentous actin reorganization and impairment of cell adhesion dynamics
por: Brandhagen, BreeAnn N, et al.
Publicado: (2013)

Synergistic effects of mifepristone on the cytotoxicity of cisplatin in cervical carcinoma cell lines and tumors grown in athymic mice
por: Jurado, Rafael, et al.
Publicado: (2007)

SOX17 increases the cisplatin sensitivity of an endometrial cancer cell line
por: Zhang, Yongli, et al.
Publicado: (2016)

Napabucasin overcomes cisplatin resistance in ovarian germ cell tumor-derived cell line by inhibiting cancer stemness
por: Schmidtova, Silvia, et al.
Publicado: (2020)

Dimethylsulfoxide excerbates cisplatin-induced cytotoxicity in Ehrlich ascites carcinoma cells
por: Osman, Abdel-Moneim M., et al.
Publicado: (2015)

Sensitivity to cisplatin in primary cell lines derived from human glioma correlates with levels of EGR-1 expression
por: Calogero, Antonella, et al.
Publicado: (2011)

The small molecule NSC676914A is cytotoxic and differentially affects NFκB signaling in ovarian cancer cells and HEK293 cells
por: Sagher, Ethan, et al.
Publicado: (2014)

Nelfinavir Induces Cytotoxicity towards High-Grade Serous Ovarian Cancer Cells, Involving Induction of the Unfolded Protein Response, Modulation of Protein Synthesis, DNA Damage, Lysosomal Impairment, and Potentiation of Toxicity Caused by Proteasome Inhibition
por: Subeha, Mahbuba R., et al.
Publicado: (2021)

High-Grade Serous Ovarian Cancer: Basic Sciences, Clinical and Therapeutic Standpoints
por: Lisio, Michael-Antony, et al.
Publicado: (2019)

Exogenous estradiol enhances apoptosis in regressing post-partum rat corpora lutea possibly mediated by prolactin
por: Goyeneche, Alicia A, et al.
Publicado: (2005)

Antiprogestins in gynecological diseases
por: Goyeneche, Alicia A, et al.
Publicado: (2015)

Hymenialdisine is Cytotoxic Against Cisplatin-Sensitive but Not Against Cisplatin-Resistant Cell Lines
por: Abdullah, Nada, et al.
Publicado: (2021)

Modulation of doxorubicin cytotoxicity by resveratrol in a human breast cancer cell line
por: Osman, Abdel-Moneim M, et al.
Publicado: (2012)

Molecular mechanisms of heptaplatin effective against cisplatin-resistant cancer cell lines: less involvement of metallothionein
por: Choi, Cheol-Hee, et al.
Publicado: (2004)

Activating Transcription Factor 3 regulates in part the enhanced tumour cell cytotoxicity of the histone deacetylase inhibitor M344 and cisplatin in combination
por: St Germain, Carly, et al.
Publicado: (2010)

Kaempferol enhances cisplatin's effect on ovarian cancer cells through promoting apoptosis caused by down regulation of cMyc
por: Luo, Haitao, et al.
Publicado: (2010)

miR-133a targets YES1 to reduce cisplatin resistance in ovarian cancer by regulating cell autophagy
por: Zhou, Yang, et al.
Publicado: (2022)

Ovarian cyst removal influences ovarian reserve dependent on histology, size and type of operation
por: Henes, Melanie, et al.
Publicado: (2018)

MiR-1244 sensitizes the resistance of non-small cell lung cancer A549 cell to cisplatin
por: Li, Weili, et al.
Publicado: (2016)

Apatinib suppresses tumor progression and enhances cisplatin sensitivity in esophageal cancer via the Akt/β-catenin pathway
por: Wei, Bin, et al.
Publicado: (2020)

Pharmacokinetics and Anti-Tumor Efficacy of PEGylated Liposomes Co-Loaded with Cisplatin and Mifepristone
por: Ocaña-Arakachi, Karen, et al.
Publicado: (2023)

Decytabine enhances cytotoxicity induced by oxaliplatin and 5-fluorouracil in the colorectal cancer cell line Colo-205
por: Flis, Sylwia, et al.
Publicado: (2009)

Cisplatin-resistant A549 non-small cell lung cancer cells can be identified by increased mitochondrial mass and are sensitive to pemetrexed treatment
por: Gao, Yanyun, et al.
Publicado: (2019)

Medication Abortion With Pharmacist Dispensing of Mifepristone
por: Grossman, Daniel, et al.
Publicado: (2021)

ETS1 is associated with cisplatin resistance through IKKα/NF-κB pathway in cell line MDA-MB-231
por: Zhang, Yuzhu, et al.
Publicado: (2018)

Analyzing the whole-transcriptome profiles of ncRNAs and predicting the competing endogenous RNA networks in cervical cancer cell lines with cisplatin resistance
por: Lv, Huimin, et al.
Publicado: (2021)

Chemosensitizing and nephroprotective effect of resveratrol in cisplatin –treated animals
por: Osman, Abdel-Moneim M, et al.
Publicado: (2015)

Cell-cycle synchronization reverses Taxol resistance of human ovarian cancer cell lines
por: Wang, Xueqing, et al.
Publicado: (2013)

Cancer-associated fibroblast-derived exosomal microRNA-98-5p promotes cisplatin resistance in ovarian cancer by targeting CDKN1A
por: Guo, Hua, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_c9o8jkfps7udf8c0cl35ii0pt9