Molecular models of human P-glycoprotein in two different catalytic states

BACKGROUND: P-glycoprotein belongs to the family of ATP-binding cassette proteins which hydrolyze ATP to catalyse the translocation of their substrates through membranes. This protein extrudes a large range of components out of cells, especially therapeutic agents causing a phenomenon known as multi...

Descripción completa

Detalles Bibliográficos
Autores principales: Becker, Jean-Paul, Depret, Grégoire, Van Bambeke, Françoise, Tulkens, Paul M, Prévost, Martine
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661087/
https://www.ncbi.nlm.nih.gov/pubmed/19159494
http://dx.doi.org/10.1186/1472-6807-9-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661087/
https://www.ncbi.nlm.nih.gov/pubmed/19159494
http://dx.doi.org/10.1186/1472-6807-9-3

Ejemplares similares