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Molecular models of human P-glycoprotein in two different catalytic states

BACKGROUND: P-glycoprotein belongs to the family of ATP-binding cassette proteins which hydrolyze ATP to catalyse the translocation of their substrates through membranes. This protein extrudes a large range of components out of cells, especially therapeutic agents causing a phenomenon known as multi...

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Detalles Bibliográficos
Autores principales:	Becker, Jean-Paul, Depret, Grégoire, Van Bambeke, Françoise, Tulkens, Paul M, Prévost, Martine
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661087/ https://www.ncbi.nlm.nih.gov/pubmed/19159494 http://dx.doi.org/10.1186/1472-6807-9-3

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