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The Early Apoptotic DNA Fragmentation Targets a Small Number of Specific Open Chromatin Regions

We report here that early apoptotic DNA fragmentation, as obtained by using an entirely new approach, is the result of an attack at a small number of specific open chromatin regions of interphase nuclei. This was demonstrated as follows: (i) chicken liver was excised and kept in sterile tubes for 1...

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Detalles Bibliográficos
Autores principales: Di Filippo, Miriam, Bernardi, Giorgio
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661134/
https://www.ncbi.nlm.nih.gov/pubmed/19347039
http://dx.doi.org/10.1371/journal.pone.0005010