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Meta-Analysis of Genome-Wide Scans for Human Adult Stature Identifies Novel Loci and Associations with Measures of Skeletal Frame Size

Recent genome-wide (GW) scans have identified several independent loci affecting human stature, but their contribution through the different skeletal components of height is still poorly understood. We carried out a genome-wide scan in 12,611 participants, followed by replication in an additional 7,...

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Detalles Bibliográficos
Autores principales: Soranzo, Nicole, Rivadeneira, Fernando, Chinappen-Horsley, Usha, Malkina, Ida, Richards, J. Brent, Hammond, Naomi, Stolk, Lisette, Nica, Alexandra, Inouye, Michael, Hofman, Albert, Stephens, Jonathan, Wheeler, Eleanor, Arp, Pascal, Gwilliam, Rhian, Jhamai, P. Mila, Potter, Simon, Chaney, Amy, Ghori, Mohammed J. R., Ravindrarajah, Radhi, Ermakov, Sergey, Estrada, Karol, Pols, Huibert A. P., Williams, Frances M., McArdle, Wendy L., van Meurs, Joyce B., Loos, Ruth J. F., Dermitzakis, Emmanouil T., Ahmadi, Kourosh R., Hart, Deborah J., Ouwehand, Willem H., Wareham, Nicholas J., Barroso, Inês, Sandhu, Manjinder S., Strachan, David P., Livshits, Gregory, Spector, Timothy D., Uitterlinden, André G., Deloukas, Panos
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661236/
https://www.ncbi.nlm.nih.gov/pubmed/19343178
http://dx.doi.org/10.1371/journal.pgen.1000445