Multiple Origins and Regional Dispersal of Resistant dhps in African Plasmodium falciparum Malaria

BACKGROUND: Although the molecular basis of resistance to a number of common antimalarial drugs is well known, a geographic description of the emergence and dispersal of resistance mutations across Africa has not been attempted. To that end we have characterised the evolutionary origins of antifolat...

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Detalles Bibliográficos
Autores principales: Pearce, Richard J., Pota, Hirva, Evehe, Marie-Solange B., Bâ, El-Hadj, Mombo-Ngoma, Ghyslain, Malisa, Allen L., Ord, Rosalynn, Inojosa, Walter, Matondo, Alexandre, Diallo, Diadier A., Mbacham, Wilfred, van den Broek, Ingrid V., Swarthout, Todd D., Getachew, Asefaw, Dejene, Seyoum, Grobusch, Martin P., Njie, Fanta, Dunyo, Samuel, Kweku, Margaret, Owusu-Agyei, Seth, Chandramohan, Daniel, Bonnet, Maryline, Guthmann, Jean-Paul, Clarke, Sian, Barnes, Karen I., Streat, Elizabeth, Katokele, Stark T., Uusiku, Petrina, Agboghoroma, Chris O., Elegba, Olufunmilayo Y., Cissé, Badara, A-Elbasit, Ishraga E., Giha, Hayder A., Kachur, S. Patrick, Lynch, Caroline, Rwakimari, John B., Chanda, Pascalina, Hawela, Moonga, Sharp, Brian, Naidoo, Inbarani, Roper, Cally
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661256/
https://www.ncbi.nlm.nih.gov/pubmed/19365539
http://dx.doi.org/10.1371/journal.pmed.1000055

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