Drugs targeting the mitochondrial pore act as citotoxic and cytostatic agents in temozolomide-resistant glioma cells

BACKGROUND: High grade gliomas are one of the most difficult cancers to treat and despite surgery, radiotherapy and temozolomide-based chemotherapy, the prognosis of glioma patients is poor. Resistance to temozolomide is the major barrier to effective therapy. Alternative therapeutic approaches have...

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Detalles Bibliográficos
Autores principales: Lena, Annalisa, Rechichi, Mariarosa, Salvetti, Alessandra, Bartoli, Barbara, Vecchio, Donatella, Scarcelli, Vittoria, Amoroso, Rosina, Benvenuti, Lucia, Gagliardi, Rolando, Gremigni, Vittorio, Rossi, Leonardo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661321/
https://www.ncbi.nlm.nih.gov/pubmed/19196452
http://dx.doi.org/10.1186/1479-5876-7-13

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