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Transcription Initiation Activity Sets Replication Origin Efficiency in Mammalian Cells
Genomic mapping of DNA replication origins (ORIs) in mammals provides a powerful means for understanding the regulatory complexity of our genome. Here we combine a genome-wide approach to identify preferential sites of DNA replication initiation at 0.4% of the mouse genome with detailed molecular an...
Autores principales: | Sequeira-Mendes, Joana, Díaz-Uriarte, Ramón, Apedaile, Anwyn, Huntley, Derek, Brockdorff, Neil, Gómez, María |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661365/ https://www.ncbi.nlm.nih.gov/pubmed/19360092 http://dx.doi.org/10.1371/journal.pgen.1000446 |
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