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Immunodominant HIV-1 Cd4+ T Cell Epitopes in Chronic Untreated Clade C HIV-1 Infection

BACKGROUND: A dominance of Gag-specific CD8+ T cell responses is significantly associated with a lower viral load in individuals with chronic, untreated clade C human immunodeficiency virus type 1 (HIV-1) infection. This association has not been investigated in terms of Gag-specific CD4+ T cell resp...

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Detalles Bibliográficos
Autores principales: Ramduth, Danni, Day, Cheryl L., Thobakgale, Christina F., Mkhwanazi, Nompumelelo P., de Pierres, Chantal, Reddy, Sharon, van der Stok, Mary, Mncube, Zenele, Nair, Kriebashne, Moodley, Eshia S., Kaufmann, Daniel E., Streeck, Hendrik, Coovadia, Hoosen M., Kiepiela, Photini, Goulder, Philip J. R., Walker, Bruce D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661367/
https://www.ncbi.nlm.nih.gov/pubmed/19352428
http://dx.doi.org/10.1371/journal.pone.0005013