Protective Effect of Perindopril on Diabetic Retinopathy Is Associated With Decreased Vascular Endothelial Growth Factor–to–Pigment Epithelium–Derived Factor Ratio: Involvement of a Mitochondria–Reactive Oxygen Species Pathway

OBJECTIVE: This study aimed to verify whether the decreased vascular endothelial growth factor (VEGF)–to–pigment epithelium–derived factor (PEDF) ratio can serve as an indicator for the protective effect of angiotensin-converting enzyme inhibitors (ACEIs) on diabetic retinopathy (DR) and to investig...

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Detalles Bibliográficos
Autores principales: Zheng, Zhi, Chen, Haibing, Ke, Genjie, Fan, Ying, Zou, Haidong, Sun, Xiaodong, Gu, Qing, Xu, Xun, Ho, Patrick C.P.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661575/
https://www.ncbi.nlm.nih.gov/pubmed/19188429
http://dx.doi.org/10.2337/db07-1524

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