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Functional Characterization of Promoter Variants of the Adiponectin Gene Complemented by Epidemiological Data
OBJECTIVE: Adiponectin (APM1, ACDC) is an adipocyte-derived protein with downregulated expression in obesity and insulin-resistant states. Several potentially regulatory single nucleotide polymorphisms (SNPs) within the APM1 gene promoter region have been associated with circulating adiponectin leve...
Autores principales: | Laumen, Helmut, Saningong, Akuma D., Heid, Iris M., Hess, Jochen, Herder, Christian, Claussnitzer, Melina, Baumert, Jens, Lamina, Claudia, Rathmann, Wolfgang, Sedlmeier, Eva-Maria, Klopp, Norman, Thorand, Barbara, Wichmann, H.-Erich, Illig, Thomas, Hauner, Hans |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661577/ https://www.ncbi.nlm.nih.gov/pubmed/19074982 http://dx.doi.org/10.2337/db07-1646 |
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