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FOXO1 Plays an Important Role in Enhanced Microvascular Cell Apoptosis and Microvascular Cell Loss in Type 1 and Type 2 Diabetic Rats

OBJECTIVE: To investigate early events leading to microvascular cell loss in diabetic retinopathy. RESEARCH DESIGN AND METHODS: FOXO1 was tested in vivo by DNA binding activity and by nuclear translocation in microvascular cells in retinal trypsin digests. In vivo studies were undertaken in STZ-indu...

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Detalles Bibliográficos
Autores principales:	Behl, Yugal, Krothapalli, Padmaja, Desta, Tesfahun, Roy, Sayon, Graves, Dana T.
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2009
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661587/ https://www.ncbi.nlm.nih.gov/pubmed/19168598 http://dx.doi.org/10.2337/db08-0537

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