Pharmacological Stimulation of NADH Oxidation Ameliorates Obesity and Related Phenotypes in Mice

OBJECTIVE: Nicotinamide adenine dinucleotides (NAD(+) and NADH) play a crucial role in cellular energy metabolism, and a dysregulated NAD(+)-to-NADH ratio is implicated in metabolic syndrome. However, it is still unknown whether a modulating intracellular NAD(+)-to-NADH ratio is beneficial in treati...

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Detalles Bibliográficos
Autores principales: Hwang, Jung Hwan, Kim, Dong Wook, Jo, Eun Jin, Kim, Yong Kyung, Jo, Young Suk, Park, Ji Hoon, Yoo, Sang Ku, Park, Myung Kyu, Kwak, Tae Hwan, Kho, Young Lim, Han, Jin, Choi, Hueng-Sik, Lee, Sang-Hee, Kim, Jin Man, Lee, InKyu, Kyung, Taeyoon, Jang, Cholsoon, Chung, Jongkyeong, Kweon, Gi Ryang, Shong, Minho
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661596/
https://www.ncbi.nlm.nih.gov/pubmed/19136651
http://dx.doi.org/10.2337/db08-1183

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