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Rapamycin Prevents and Breaks the Anti-CD3–Induced Tolerance in NOD Mice
OBJECTIVE: Non–Fc-binding anti-CD3–specific antibodies represent a promising therapy for preserving C-peptide production in subjects with recent-onset type 1 diabetes. However, the mechanisms by which anti-CD3 exerts its beneficial effect are still poorly understood, and it is questionable whether t...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
American Diabetes Association
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661605/ https://www.ncbi.nlm.nih.gov/pubmed/19151201 http://dx.doi.org/10.2337/db08-1432 |