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Association of constitutively activated hepatocyte growth factor receptor (Met) with resistance to a dual EGFR/Her2 inhibitor in non-small-cell lung cancer cells

There is a pressing need to identify new drug targets and novel approaches for treatment of non-small-cell lung carcinoma (NSCLC). Members of the epidermal growth factor receptor (EGFR) and Met receptor families have been identified as important molecular targets for NSCLC. Two EGFR tyrosine kinase...

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Detalles Bibliográficos
Autores principales:	Agarwal, S, Zerillo, C, Kolmakova, J, Christensen, J G, Harris, L N, Rimm, D L, DiGiovanna, M P, Stern, D F
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2009
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661782/ https://www.ncbi.nlm.nih.gov/pubmed/19240716 http://dx.doi.org/10.1038/sj.bjc.6604937

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