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Diesel Exhaust Particles Activate the Matrix-Metalloproteinase-1 Gene in Human Bronchial Epithelia in a β-Arrestin–Dependent Manner via Activation of RAS
BACKGROUND: Diesel exhaust particles (DEPs) are globally relevant air pollutants that exert a detrimental human health impact. However, mechanisms of damage by DEP exposure to human respiratory health and human susceptibility factors are only partially known. Matrix metalloproteinase-1 (MMP-1) has b...
Autores principales: | Li, Jinju, Ghio, Andrew J., Cho, Seung-Hyun, Brinckerhoff, Constance E., Simon, Sidney A., Liedtke, Wolfgang |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
National Institute of Environmental Health Sciences
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661910/ https://www.ncbi.nlm.nih.gov/pubmed/19337515 http://dx.doi.org/10.1289/ehp.0800311 |
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