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Diesel Exhaust Particles Activate the Matrix-Metalloproteinase-1 Gene in Human Bronchial Epithelia in a β-Arrestin–Dependent Manner via Activation of RAS

BACKGROUND: Diesel exhaust particles (DEPs) are globally relevant air pollutants that exert a detrimental human health impact. However, mechanisms of damage by DEP exposure to human respiratory health and human susceptibility factors are only partially known. Matrix metalloproteinase-1 (MMP-1) has b...

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Detalles Bibliográficos
Autores principales: Li, Jinju, Ghio, Andrew J., Cho, Seung-Hyun, Brinckerhoff, Constance E., Simon, Sidney A., Liedtke, Wolfgang
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661910/
https://www.ncbi.nlm.nih.gov/pubmed/19337515
http://dx.doi.org/10.1289/ehp.0800311

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