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Perioperative and Oncological Outcome of Laparoscopic Resection of Gastrointestinal Stromal Tumour (GIST) of the Stomach

Background. Surgery remains the only curative treatment for gastrointestinal stromal tumour (GIST). Resection needs to ensure tumour-free margins while lymphadenectomy is not required. Thus, partial gastric resection is the treatment of choice for small gastric GISTs. Evidence on whether performing...

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Autores principales: Ronellenfitsch, Ulrich, Staiger, Wilko, Kähler, Georg, Ströbel, Philipp, Schwarzbach, Matthias, Hohenberger, Peter
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2662319/
https://www.ncbi.nlm.nih.gov/pubmed/19343179
http://dx.doi.org/10.1155/2009/286138
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author Ronellenfitsch, Ulrich
Staiger, Wilko
Kähler, Georg
Ströbel, Philipp
Schwarzbach, Matthias
Hohenberger, Peter
author_facet Ronellenfitsch, Ulrich
Staiger, Wilko
Kähler, Georg
Ströbel, Philipp
Schwarzbach, Matthias
Hohenberger, Peter
author_sort Ronellenfitsch, Ulrich
collection PubMed
description Background. Surgery remains the only curative treatment for gastrointestinal stromal tumour (GIST). Resection needs to ensure tumour-free margins while lymphadenectomy is not required. Thus, partial gastric resection is the treatment of choice for small gastric GISTs. Evidence on whether performing resection laparoscopically compromises outcome is limited. Methods. We compiled patients undergoing laparoscopic resection of suspected gastric GIST between 2003 and 2007. Follow-up was performed to obtain information on tumour recurrence. Results. Laparoscopic resection with free margins was performed in 21/22 patients. Histology confirmed GIST in 17 cases, 4 tumours were benign neoplasms. Median operation time and postoperative stay for GIST patients were 130 (range 80–201) mins and 7 (range 5–95) days. Two patients experienced stapler line leakage necessitating surgical revision. After median follow-up of 18 (range 1–53) months, no recurrence occurred. Conclusions. Laparoscopic resection of gastric GISTs yields good perioperative outcomes. Oncologic outcome needs to be assessed with longer follow-up. For posterior lesions, special precaution is needed. Laparoscopic resection could become standard for circumscribed gastric GISTs if necessary precautions for oncological procedures are observed.
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spelling pubmed-26623192009-04-02 Perioperative and Oncological Outcome of Laparoscopic Resection of Gastrointestinal Stromal Tumour (GIST) of the Stomach Ronellenfitsch, Ulrich Staiger, Wilko Kähler, Georg Ströbel, Philipp Schwarzbach, Matthias Hohenberger, Peter Diagn Ther Endosc Clinical Study Background. Surgery remains the only curative treatment for gastrointestinal stromal tumour (GIST). Resection needs to ensure tumour-free margins while lymphadenectomy is not required. Thus, partial gastric resection is the treatment of choice for small gastric GISTs. Evidence on whether performing resection laparoscopically compromises outcome is limited. Methods. We compiled patients undergoing laparoscopic resection of suspected gastric GIST between 2003 and 2007. Follow-up was performed to obtain information on tumour recurrence. Results. Laparoscopic resection with free margins was performed in 21/22 patients. Histology confirmed GIST in 17 cases, 4 tumours were benign neoplasms. Median operation time and postoperative stay for GIST patients were 130 (range 80–201) mins and 7 (range 5–95) days. Two patients experienced stapler line leakage necessitating surgical revision. After median follow-up of 18 (range 1–53) months, no recurrence occurred. Conclusions. Laparoscopic resection of gastric GISTs yields good perioperative outcomes. Oncologic outcome needs to be assessed with longer follow-up. For posterior lesions, special precaution is needed. Laparoscopic resection could become standard for circumscribed gastric GISTs if necessary precautions for oncological procedures are observed. Hindawi Publishing Corporation 2009 2009-03-26 /pmc/articles/PMC2662319/ /pubmed/19343179 http://dx.doi.org/10.1155/2009/286138 Text en Copyright © 2009 Ulrich Ronellenfitsch et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Ronellenfitsch, Ulrich
Staiger, Wilko
Kähler, Georg
Ströbel, Philipp
Schwarzbach, Matthias
Hohenberger, Peter
Perioperative and Oncological Outcome of Laparoscopic Resection of Gastrointestinal Stromal Tumour (GIST) of the Stomach
title Perioperative and Oncological Outcome of Laparoscopic Resection of Gastrointestinal Stromal Tumour (GIST) of the Stomach
title_full Perioperative and Oncological Outcome of Laparoscopic Resection of Gastrointestinal Stromal Tumour (GIST) of the Stomach
title_fullStr Perioperative and Oncological Outcome of Laparoscopic Resection of Gastrointestinal Stromal Tumour (GIST) of the Stomach
title_full_unstemmed Perioperative and Oncological Outcome of Laparoscopic Resection of Gastrointestinal Stromal Tumour (GIST) of the Stomach
title_short Perioperative and Oncological Outcome of Laparoscopic Resection of Gastrointestinal Stromal Tumour (GIST) of the Stomach
title_sort perioperative and oncological outcome of laparoscopic resection of gastrointestinal stromal tumour (gist) of the stomach
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2662319/
https://www.ncbi.nlm.nih.gov/pubmed/19343179
http://dx.doi.org/10.1155/2009/286138
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