A Fluorous-Tagged “Safety Catch” Linker for Preparing Heterocycles by Ring-Closing Metathesis

[Image: see text] A fluorous-tagged “safety catch” linker is described for the synthesis of heterocycles with use of ring-closing metathesis. The linker facilitiates the purification of metathesis substrates, the removal of the catalyst, the functionalization of the products, and the release of only...

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Autores principales: O’Leary-Steele, Catherine, Cordier, Christopher, Hayes, Jerome, Warriner, Stuart, Nelson, Adam
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2009
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2662370/
https://www.ncbi.nlm.nih.gov/pubmed/19173645
http://dx.doi.org/10.1021/ol802848j
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author O’Leary-Steele, Catherine
Cordier, Christopher
Hayes, Jerome
Warriner, Stuart
Nelson, Adam
author_facet O’Leary-Steele, Catherine
Cordier, Christopher
Hayes, Jerome
Warriner, Stuart
Nelson, Adam
author_sort O’Leary-Steele, Catherine
collection PubMed
description [Image: see text] A fluorous-tagged “safety catch” linker is described for the synthesis of heterocycles with use of ring-closing metathesis. The linker facilitiates the purification of metathesis substrates, the removal of the catalyst, the functionalization of the products, and the release of only metathesis products. The synthesis of a range of heterocycles is described.
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spelling pubmed-26623702009-03-30 A Fluorous-Tagged “Safety Catch” Linker for Preparing Heterocycles by Ring-Closing Metathesis O’Leary-Steele, Catherine Cordier, Christopher Hayes, Jerome Warriner, Stuart Nelson, Adam Org Lett [Image: see text] A fluorous-tagged “safety catch” linker is described for the synthesis of heterocycles with use of ring-closing metathesis. The linker facilitiates the purification of metathesis substrates, the removal of the catalyst, the functionalization of the products, and the release of only metathesis products. The synthesis of a range of heterocycles is described. American Chemical Society 2009-01-27 2009-02-19 /pmc/articles/PMC2662370/ /pubmed/19173645 http://dx.doi.org/10.1021/ol802848j Text en Copyright © 2009 American Chemical Society http://pubs.acs.org This is an open-access article distributed under the ACS AuthorChoice Terms & Conditions. Any use of this article, must conform to the terms of that license which are available at http://pubs.acs.org.
spellingShingle O’Leary-Steele, Catherine
Cordier, Christopher
Hayes, Jerome
Warriner, Stuart
Nelson, Adam
A Fluorous-Tagged “Safety Catch” Linker for Preparing Heterocycles by Ring-Closing Metathesis
title A Fluorous-Tagged “Safety Catch” Linker for Preparing Heterocycles by Ring-Closing Metathesis
title_full A Fluorous-Tagged “Safety Catch” Linker for Preparing Heterocycles by Ring-Closing Metathesis
title_fullStr A Fluorous-Tagged “Safety Catch” Linker for Preparing Heterocycles by Ring-Closing Metathesis
title_full_unstemmed A Fluorous-Tagged “Safety Catch” Linker for Preparing Heterocycles by Ring-Closing Metathesis
title_short A Fluorous-Tagged “Safety Catch” Linker for Preparing Heterocycles by Ring-Closing Metathesis
title_sort fluorous-tagged “safety catch” linker for preparing heterocycles by ring-closing metathesis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2662370/
https://www.ncbi.nlm.nih.gov/pubmed/19173645
http://dx.doi.org/10.1021/ol802848j
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