Involvement of Raft Aggregates Enriched in Fas/CD95 Death-Inducing Signaling Complex in the Antileukemic Action of Edelfosine in Jurkat Cells

BACKGROUND: Recent evidence suggests that co-clustering of Fas/CD95 death receptor and lipid rafts plays a major role in death receptor-mediated apoptosis. METHODOLOGY/PRINCIPAL FINDINGS: By a combination of genetic, biochemical, and ultrastructural approaches, we provide here compelling evidence fo...

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Detalles Bibliográficos
Autores principales: Gajate, Consuelo, Gonzalez-Camacho, Fernando, Mollinedo, Faustino
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2662410/
https://www.ncbi.nlm.nih.gov/pubmed/19352436
http://dx.doi.org/10.1371/journal.pone.0005044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2662410/
https://www.ncbi.nlm.nih.gov/pubmed/19352436
http://dx.doi.org/10.1371/journal.pone.0005044

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