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The Anti-Apoptotic Activity of BAG3 Is Restricted by Caspases and the Proteasome
BACKGROUND: Caspase-mediated cleavage and proteasomal degradation of ubiquitinated proteins are two independent mechanisms for the regulation of protein stability and cellular function. We previously reported BAG3 overexpression protected ubiquitinated clients, such as AKT, from proteasomal degradat...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2662420/ https://www.ncbi.nlm.nih.gov/pubmed/19352495 http://dx.doi.org/10.1371/journal.pone.0005136 |