Impact of Deoxynivalenol on the Intestinal Microflora of Pigs

Deoxynivalenol (DON), a mycotoxin produced by some Fusarium species, is a frequent contaminant of cereal. In the present study, 24 weanling piglets received either control feed or feed naturally contaminated with DON (2.8 mg/kg) for four weeks. Consumption of contaminated feed significantly reduced...

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Detalles Bibliográficos
Autores principales: Waché, Yann J., Valat, Charlotte, Postollec, Gilbert, Bougeard, Stephanie, Burel, Christine, Oswald, Isabelle P., Fravalo, Philippe
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2662463/
https://www.ncbi.nlm.nih.gov/pubmed/19333431
http://dx.doi.org/10.3390/ijms10010001
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author Waché, Yann J.
Valat, Charlotte
Postollec, Gilbert
Bougeard, Stephanie
Burel, Christine
Oswald, Isabelle P.
Fravalo, Philippe
author_facet Waché, Yann J.
Valat, Charlotte
Postollec, Gilbert
Bougeard, Stephanie
Burel, Christine
Oswald, Isabelle P.
Fravalo, Philippe
author_sort Waché, Yann J.
collection PubMed
description Deoxynivalenol (DON), a mycotoxin produced by some Fusarium species, is a frequent contaminant of cereal. In the present study, 24 weanling piglets received either control feed or feed naturally contaminated with DON (2.8 mg/kg) for four weeks. Consumption of contaminated feed significantly reduced the animal weight gain during the first week of the experiment, but had a moderate effect on cultivable bacteria in the pig intestine. By contrast, changes in the intestinal microflora were observed by Capillary Electrophoresis Single-Stranded Conformation Polymorphism (CE-SSCP) in DON-exposed animals, suggesting an impact of this toxin on the dynamics of intestinal bacteria communities.
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spelling pubmed-26624632009-03-30 Impact of Deoxynivalenol on the Intestinal Microflora of Pigs Waché, Yann J. Valat, Charlotte Postollec, Gilbert Bougeard, Stephanie Burel, Christine Oswald, Isabelle P. Fravalo, Philippe Int J Mol Sci Article Deoxynivalenol (DON), a mycotoxin produced by some Fusarium species, is a frequent contaminant of cereal. In the present study, 24 weanling piglets received either control feed or feed naturally contaminated with DON (2.8 mg/kg) for four weeks. Consumption of contaminated feed significantly reduced the animal weight gain during the first week of the experiment, but had a moderate effect on cultivable bacteria in the pig intestine. By contrast, changes in the intestinal microflora were observed by Capillary Electrophoresis Single-Stranded Conformation Polymorphism (CE-SSCP) in DON-exposed animals, suggesting an impact of this toxin on the dynamics of intestinal bacteria communities. Molecular Diversity Preservation International (MDPI) 2008-12-27 /pmc/articles/PMC2662463/ /pubmed/19333431 http://dx.doi.org/10.3390/ijms10010001 Text en © 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Waché, Yann J.
Valat, Charlotte
Postollec, Gilbert
Bougeard, Stephanie
Burel, Christine
Oswald, Isabelle P.
Fravalo, Philippe
Impact of Deoxynivalenol on the Intestinal Microflora of Pigs
title Impact of Deoxynivalenol on the Intestinal Microflora of Pigs
title_full Impact of Deoxynivalenol on the Intestinal Microflora of Pigs
title_fullStr Impact of Deoxynivalenol on the Intestinal Microflora of Pigs
title_full_unstemmed Impact of Deoxynivalenol on the Intestinal Microflora of Pigs
title_short Impact of Deoxynivalenol on the Intestinal Microflora of Pigs
title_sort impact of deoxynivalenol on the intestinal microflora of pigs
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2662463/
https://www.ncbi.nlm.nih.gov/pubmed/19333431
http://dx.doi.org/10.3390/ijms10010001
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