Severe Dengue Epidemics in Sri Lanka, 2003–2006

Recent emergence of dengue hemorrhagic fever in the Indian subcontinent has been well documented in Sri Lanka. We compare recent (2003–2006) and past (1980–1997) dengue surveillance data for Sri Lanka. The 4 dengue virus (DENV) serotypes have been cocirculating in Sri Lanka for >30 years. Over th...

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Autores principales: Kanakaratne, Nalaka, Wahala, Wahala M.P.B., Messer, William B., Tissera, Hasitha A., Shahani, Aruna, Abeysinghe, Nihal, de Silva, Aravinda M., Gunasekera, Maya
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2662655/
https://www.ncbi.nlm.nih.gov/pubmed/19193262
http://dx.doi.org/10.3201/eid1502.080926
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author Kanakaratne, Nalaka
Wahala, Wahala M.P.B.
Messer, William B.
Tissera, Hasitha A.
Shahani, Aruna
Abeysinghe, Nihal
de Silva, Aravinda M.
Gunasekera, Maya
author_facet Kanakaratne, Nalaka
Wahala, Wahala M.P.B.
Messer, William B.
Tissera, Hasitha A.
Shahani, Aruna
Abeysinghe, Nihal
de Silva, Aravinda M.
Gunasekera, Maya
author_sort Kanakaratne, Nalaka
collection PubMed
description Recent emergence of dengue hemorrhagic fever in the Indian subcontinent has been well documented in Sri Lanka. We compare recent (2003–2006) and past (1980–1997) dengue surveillance data for Sri Lanka. The 4 dengue virus (DENV) serotypes have been cocirculating in Sri Lanka for >30 years. Over this period, a new genotype of DENV-1 has replaced an old genotype. Moreover, new clades of DENV-3 genotype III viruses have replaced older clades. Emergence of new clades of DENV-3 in 1989 and 2000 coincided with abrupt increases in the number of reported dengue cases, implicating this serotype in severe epidemics. In 1980–1997, most reported dengue cases were in children. Recent epidemics have been characterized by many cases in children and adults. Changes in local transmission dynamics and genetic changes in DENV-3 are likely increasing emergence of severe dengue epidemics in Sri Lanka.
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spelling pubmed-26626552009-03-30 Severe Dengue Epidemics in Sri Lanka, 2003–2006 Kanakaratne, Nalaka Wahala, Wahala M.P.B. Messer, William B. Tissera, Hasitha A. Shahani, Aruna Abeysinghe, Nihal de Silva, Aravinda M. Gunasekera, Maya Emerg Infect Dis Research Recent emergence of dengue hemorrhagic fever in the Indian subcontinent has been well documented in Sri Lanka. We compare recent (2003–2006) and past (1980–1997) dengue surveillance data for Sri Lanka. The 4 dengue virus (DENV) serotypes have been cocirculating in Sri Lanka for >30 years. Over this period, a new genotype of DENV-1 has replaced an old genotype. Moreover, new clades of DENV-3 genotype III viruses have replaced older clades. Emergence of new clades of DENV-3 in 1989 and 2000 coincided with abrupt increases in the number of reported dengue cases, implicating this serotype in severe epidemics. In 1980–1997, most reported dengue cases were in children. Recent epidemics have been characterized by many cases in children and adults. Changes in local transmission dynamics and genetic changes in DENV-3 are likely increasing emergence of severe dengue epidemics in Sri Lanka. Centers for Disease Control and Prevention 2009-02 /pmc/articles/PMC2662655/ /pubmed/19193262 http://dx.doi.org/10.3201/eid1502.080926 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research
Kanakaratne, Nalaka
Wahala, Wahala M.P.B.
Messer, William B.
Tissera, Hasitha A.
Shahani, Aruna
Abeysinghe, Nihal
de Silva, Aravinda M.
Gunasekera, Maya
Severe Dengue Epidemics in Sri Lanka, 2003–2006
title Severe Dengue Epidemics in Sri Lanka, 2003–2006
title_full Severe Dengue Epidemics in Sri Lanka, 2003–2006
title_fullStr Severe Dengue Epidemics in Sri Lanka, 2003–2006
title_full_unstemmed Severe Dengue Epidemics in Sri Lanka, 2003–2006
title_short Severe Dengue Epidemics in Sri Lanka, 2003–2006
title_sort severe dengue epidemics in sri lanka, 2003–2006
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2662655/
https://www.ncbi.nlm.nih.gov/pubmed/19193262
http://dx.doi.org/10.3201/eid1502.080926
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