Characterization of NF-kB-mediated inhibition of catechol-O-methyltransferase

BACKGROUND: Catechol-O-methyltransferase (COMT), an enzyme that metabolizes catecholamines, has recently been implicated in the modulation of pain. Specifically, low COMT activity is associated with heightened pain perception and development of musculoskeletal pain in humans as well as increased exp...

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Detalles Bibliográficos
Autores principales: Tchivileva, Inna E, Nackley, Andrea G, Qian, Li, Wentworth, Sean, Conrad, Matthew, Diatchenko, Luda B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2662804/
https://www.ncbi.nlm.nih.gov/pubmed/19291302
http://dx.doi.org/10.1186/1744-8069-5-13

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