Ascorbic acid pre-treated quartz stimulates TNF-α release in RAW 264.7 murine macrophages through ROS production and membrane lipid peroxidation

BACKGROUND: Inhalation of crystalline silica induces a pulmonary fibrotic degeneration called silicosis caused by the inability of alveolar macrophages to dissolve the crystalline structure of phagocytosed quartz particles. Ascorbic acid is capable of partially dissolving quartz crystals, leading to...

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Detalles Bibliográficos
Autores principales: Scarfì, Sonia, Magnone, Mirko, Ferraris, Chiara, Pozzolini, Marina, Benvenuto, Federica, Benatti, Umberto, Giovine, Marco
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2662810/
https://www.ncbi.nlm.nih.gov/pubmed/19298665
http://dx.doi.org/10.1186/1465-9921-10-25

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2662810/
https://www.ncbi.nlm.nih.gov/pubmed/19298665
http://dx.doi.org/10.1186/1465-9921-10-25

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