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A Cytokine–Cytokine Interaction in the Assembly of Higher-Order Structure and Activation of the Interleukine-3:Receptor Complex

Interleukine-3 (IL-3) binds its receptor and initiates a cascade of signaling processes that regulate the proliferation and differentiation of hematopoietic cells. To understand the detailed mechanisms of IL-3 induced receptor activation, we generated a homology model of the IL-3:receptor complex ba...

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Detalles Bibliográficos
Autores principales: Dey, Raja, Ji, Kunmei, Liu, Zhigang, Chen, Lin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2662821/
https://www.ncbi.nlm.nih.gov/pubmed/19352505
http://dx.doi.org/10.1371/journal.pone.0005188

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