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APRIL is overexpressed in cancer: link with tumor progression

BACKGROUND: BAFF and APRIL share two receptors – TACI and BCMA – and BAFF binds to a third receptor, BAFF-R. Increased expression of BAFF and APRIL is noted in hematological malignancies. BAFF and APRIL are essential for the survival of normal and malignant B lymphocytes, and altered expression of B...

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Detalles Bibliográficos
Autores principales:	Moreaux, Jérôme, Veyrune, Jean-Luc, De Vos, John, Klein, Bernard
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2662875/ https://www.ncbi.nlm.nih.gov/pubmed/19291294 http://dx.doi.org/10.1186/1471-2407-9-83

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