Cargando…

Achieving lipid goals with rosuvastatin compared with simvastatin in high risk patients in real clinical practice: a randomized, open-label, parallel-group, multi-center study: the DISCOVERY-Beta study

The aim of this multi-center, open-label, randomized, parallel-group trial was to compare the efficacy of rosuvastatin with that of simvastatin in achieving the 1998 European Atherosclerosis Society (EAS) lipid treatment goals. 504 patients (≥18 years) with primary hypercholesterolemia and a 10-year...

Descripción completa

Detalles Bibliográficos
Autores principales:	Laks, Toivo, Keba, Ester, Leiner, Mariann, Merilind, Eero, Petersen, Mall, Reinmets, Sirje, Väli, Sille, Sööt, Terje, Otter, Karin
Formato:	Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2008
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2663459/ https://www.ncbi.nlm.nih.gov/pubmed/19337553

Ejemplares similares

Changes in LDL-C levels and goal attainment associated with addition of ezetimibe to simvastatin, atorvastatin, or rosuvastatin compared with titrating statin monotherapy
por: Foody, JoAnne M, et al.
Publicado: (2013)

Antibacterial activity of statins: a comparative study of Atorvastatin, Simvastatin, and Rosuvastatin
por: Masadeh, Majed, et al.
Publicado: (2012)

Protective effect of simvastatin and rosuvastatin on trinitrobenzene sulfonic acid-induced colitis in rats
por: Maheshwari, Rajesh A., et al.
Publicado: (2015)

Relationship between genetic polymorphism of drug transporters and the efficacy of Rosuvastatin, atorvastatin and simvastatin in patients with hyperlipidemia
por: Sivkov, Andrey, et al.
Publicado: (2021)

A comparative evaluation of safety and efficacy of rosuvastatin, simvastatin, and atorvastatin in patients of type 2 diabetes mellitus with dyslipidemia
por: Adsule, Samir Maruti, et al.
Publicado: (2009)

Cost-effectiveness of rosuvastatin in comparison with generic atorvastatin and simvastatin in a Swedish population at high risk of cardiovascular events
por: Gandhi, Sanjay K, et al.
Publicado: (2012)

Effects of ezetimibe/simvastatin 10/10 mg versus Rosuvastatin 10 mg on carotid atherosclerotic plaque inflammation
por: Oh, Minyoung, et al.
Publicado: (2019)

Moderate-Intensity Rosuvastatin Plus Ezetimibe Versus High-Intensity Rosuvastatin for Target Low-Density Lipoprotein Cholesterol Goal Achievement in Patients With Recent Ischemic Stroke: A Randomized Controlled Trial
por: Hong, Keun-Sik, et al.
Publicado: (2023)

Effects of Fostamatinib on the Pharmacokinetics of Oral Contraceptive, Warfarin, and the Statins Rosuvastatin and Simvastatin: Results From Phase I Clinical Studies
por: Martin, P., et al.
Publicado: (2016)

Effects of Ezetimibe/Simvastatin and Rosuvastatin on Oxidative Stress in Diabetic Neuropathy: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
por: Villegas-Rivera, Geannyne, et al.
Publicado: (2015)

Cost-Effectiveness Analysis of Simvastatin and Lovastatin/Extended-Release Niacin to Achieve LDL and HDL Goal Using NHANES Data
por: Armstrong, Edward P., et al.
Publicado: (2004)

Sub-gingival delivery of simvastatin and rosuvastatin for treatment of chronic periodontitis with diabetes mellitus: A randomized controlled clinical-radiographic pilot study
por: Sharma, Pallavi, et al.
Publicado: (2023)

Ezetimibe/Simvastatin 10/20 mg versus Rosuvastatin 10 mg in high-risk hypercholesterolemic patients stratified by prior statin treatment potency
por: Viigimaa, Margus, et al.
Publicado: (2010)

Comparative effectiveness of rosuvastatin versus simvastatin in primary prevention among new users: a cohort study in the French national health insurance database
por: Neumann, Anke, et al.
Publicado: (2014)

Effect of Roxadustat on the Pharmacokinetics of Simvastatin, Rosuvastatin, and Atorvastatin in Healthy Subjects: Results From 3 Phase 1, Open‐Label, 1‐Sequence, Crossover Studies
por: Groenendaal‐van de Meent, Dorien, et al.
Publicado: (2022)

Current Perspectives on rosuvastatin
por: Hu, Miao, et al.
Publicado: (2013)

Rosuvastatin and chronic hepatitis C
por: Yoshida, Eric M.
Publicado: (2011)

Rosuvastatin induced photolocalized purpura
por: Thabouti, Marwa, et al.
Publicado: (2022)

Comparison of the effect of rosuvastatin versus rosuvastatin/ezetimibe on markers of inflammation in patients with acute myocardial infarction
por: Ren, Yizhi, et al.
Publicado: (2017)

Real-World Evidence Evaluation on the Lipid Profile, Therapeutic Goals, and Safety of the Fixed-Dose Combination of Rosuvastatin/Ezetimibe (Trezete®) in Dyslipidemia Patients
por: Rodríguez-Saldaña, Joel, et al.
Publicado: (2022)

Rosuvastatin and simvastatin attenuate cisplatin-induced cardiotoxicity via disruption of endoplasmic reticulum stress-mediated apoptotic death in rats: targeting ER-Chaperone GRP78 and Calpain-1 pathways
por: Saleh, Dalia O., et al.
Publicado: (2020)

The Efficacy and Safety of Moderate-Intensity Rosuvastatin with Ezetimibe versus High-Intensity Rosuvastatin in High Atherosclerotic Cardiovascular Disease Risk Patients with Type 2 Diabetes Mellitus: A Randomized, Multicenter, Open, Parallel, Phase 4 Study
por: Moon, Jun Sung, et al.
Publicado: (2023)

Parallel hippocampal-parietal circuits for self- and goal-oriented processing
por: Zheng, Annie, et al.
Publicado: (2021)

Efficacy and safety of rosuvastatin in the management of dyslipidemia
por: Rubba, Paolo, et al.
Publicado: (2009)

Preparation and optimization of microemulsion of rosuvastatin calcium
por: Patel, Zalak B., et al.
Publicado: (2012)

Rosuvastatin-Induced Acute Interstitial Nephritis
por: Londrino, Francesco, et al.
Publicado: (2013)

The influence of the intestinal microflora to the efficacy of Rosuvastatin
por: Wang, Lijun, et al.
Publicado: (2018)

Primary prevention of coronary heart disease: integration of new data, evolving views, revised goals, and role of rosuvastatin in management. A comprehensive survey
por: Kones, Richard
Publicado: (2011)

Achieve your goals
por: Smith, Andy
Publicado: (2006)

Lipid lowering efficacy and safety of Ezetimibe combined with rosuvastatin compared with titrating rosuvastatin monotherapy in HIV-positive patients
por: Saeedi, Ramesh, et al.
Publicado: (2015)

Comparison of Ezetimibe/Simvastatin 10/20 mg Versus Atorvastatin 20 mg in Achieving a Target Low Density Lipoprotein-Cholesterol Goal for Patients With Very High Risk
por: Cho, Yun-Kyeong, et al.
Publicado: (2011)

Achievement of Lipid Targets with the Combination of Rosuvastatin and Fenofibric Acid in Patients with Type 2 Diabetes Mellitus
por: Rosenson, Robert S., et al.
Publicado: (2010)

Generation of polyclonal antibody with high avidity to rosuvastatin and its use in development of highly sensitive ELISA for determination of rosuvastatin in plasma
por: Darwish, Ibrahim A, et al.
Publicado: (2011)

Efficacy and Tolerability of a Fixed-Dose Combination of Rosuvastatin and Ezetimibe Compared with a Fixed-Dose Combination of Simvastatin and Ezetimibe in Brazilian Patients with Primary Hypercholesterolemia or Mixed Dyslipidemia: A Multicenter, Randomized Trial
por: Vattimo, Antonio Carlos Amedeo, et al.
Publicado: (2020)

Pharmacokinetic interactions and tolerability of berberine chloride with simvastatin and fenofibrate: an open-label, randomized, parallel study in healthy Chinese subjects
por: Li, Guofei, et al.
Publicado: (2018)

Ezetimibe/simvastatin vs simvastatin in coronary heart disease patients with or without diabetes
por: Rotella, Carlo M, et al.
Publicado: (2010)

Hepatotoxicity Associated with a Short Course of Rosuvastatin
por: Hwang, Na Kyoung, et al.
Publicado: (2015)

Effect and Safety of Rosuvastatin in Acute Ischemic Stroke
por: Heo, Ji Hoe, et al.
Publicado: (2016)

Examination of Physiologically‐Based Pharmacokinetic Models of Rosuvastatin
por: Bowman, Christine M., et al.
Publicado: (2020)

Exploring the molecular reorientations in amorphous rosuvastatin calcium
por: Belozerova, N. M., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_r772ghp5ldvdaoi5cstpkgluu7