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Retnla (Relmα/Fizz1) Suppresses Helminth-Induced Th2-Type Immunity

Retnla (Resistin-like molecule alpha/FIZZ1) is induced during Th2 cytokine immune responses. However, the role of Retnla in Th2-type immunity is unknown. Here, using Retnla(−/−) mice and three distinct helminth models, we show that Retnla functions as a negative regulator of Th2 responses. Pulmonary...

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Detalles Bibliográficos
Autores principales:	Pesce, John T., Ramalingam, Thirumalai R., Wilson, Mark S., Mentink-Kane, Margaret M., Thompson, Robert W., Cheever, Allen W., Urban, Joseph F., Wynn, Thomas A.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2663845/ https://www.ncbi.nlm.nih.gov/pubmed/19381262 http://dx.doi.org/10.1371/journal.ppat.1000393

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