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CD4 and CD8 T Cell Responses to the M. tuberculosis Ag85B-TB10.4 Promoted by Adjuvanted Subunit, Adenovector or Heterologous Prime Boost Vaccination

BACKGROUND: Although CD4 T cells are crucial for defense against M.tb, it is still not clear whether the optimal response against M.tb in fact involves both CD4 and CD8 T cells. To test this, we used a new vaccine strategy that generated a strong balanced T cell response consisting of both CD4 and C...

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Detalles Bibliográficos
Autores principales:	Elvang, Tara, Christensen, Jan P., Billeskov, Rolf, Thi Kim Thanh Hoang, Truc, Holst, Peter, Thomsen, Allan Randrup, Andersen, Peter, Dietrich, Jes
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2663846/ https://www.ncbi.nlm.nih.gov/pubmed/19357780 http://dx.doi.org/10.1371/journal.pone.0005139

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