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Prognostic Factors for Mortality Among Patients Above the 6(th) Decade Undergoing Non-Cardiac Surgery: (Cares – Clinical Assessment and Research in Elderly Surgical Patients)

PURPOSE: To ascertain perioperative morbimortality and identify prognostic factors for mortality among patients ≥55 years who undergo non-cardiac surgery. METHODS: A retrospective cohort of 403 patients relating to perioperative morbidity-mortality. Data were collected from a standardized protocol o...

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Autores principales: Machado, Adriana Nunes, do Carmo Sitta, Maria, Filho, Wilson Jacob, Garcez-Leme, Luíz Eugênio
Formato: Texto
Lenguaje:English
Publicado: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664206/
https://www.ncbi.nlm.nih.gov/pubmed/18438567
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author Machado, Adriana Nunes
do Carmo Sitta, Maria
Filho, Wilson Jacob
Garcez-Leme, Luíz Eugênio
author_facet Machado, Adriana Nunes
do Carmo Sitta, Maria
Filho, Wilson Jacob
Garcez-Leme, Luíz Eugênio
author_sort Machado, Adriana Nunes
collection PubMed
description PURPOSE: To ascertain perioperative morbimortality and identify prognostic factors for mortality among patients ≥55 years who undergo non-cardiac surgery. METHODS: A retrospective cohort of 403 patients relating to perioperative morbidity-mortality. Data were collected from a standardized protocol on gender, age, comorbidities, medications used, smoking, alcohol abuse, chronic use of benzodiazepine, nutritional status, presence of anemia, activities of daily living, American Society of Anesthesiology classification, Detsky’s modified cardiac risk index - American College of Physicians, renal function evaluation, pulmonary risk according to the Torrington scale, risk of thromboembolic events, presence of malignant disease and complementary examinations. RESULTS: The mean age of the subjects was 70.8 ± 8.1 years. The “very old” (≥80 years) represented 14%. The mortality rate was 8.2%, and the complication rate was 15.8%. Multiple logistic regression showed that a history of coronary heart disease (OR: 3.75; p=0.02) and/or valvular heart disease (OR: 31.79; p=0.006) were predictors of mortality. The American Society of Anesthesiology classification was shown to be the best scale to mark risk (OR: 3.01; p=0.016). Nutritional status was a protective factor, in which serum albumin increases of 1 mg/dl decreased risk by 63%. DISCUSSION: The results indicate that serum albumin, coronary heart disease, valvular heart disease and the American Society of Anesthesiology classification could be prognostic predictors for aged patients in a perioperative setting. In this sample, provided that pulmonary, cardiac and thromboembolic risks were properly controlled, they did not constitute risk factors for mortality. Furthermore, continuous effort to learn more about the preoperative assessment of elderly patients could yield intervention possibilities and minimize morbimortality.
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spelling pubmed-26642062009-05-13 Prognostic Factors for Mortality Among Patients Above the 6(th) Decade Undergoing Non-Cardiac Surgery: (Cares – Clinical Assessment and Research in Elderly Surgical Patients) Machado, Adriana Nunes do Carmo Sitta, Maria Filho, Wilson Jacob Garcez-Leme, Luíz Eugênio Clinics Clinical Sciences PURPOSE: To ascertain perioperative morbimortality and identify prognostic factors for mortality among patients ≥55 years who undergo non-cardiac surgery. METHODS: A retrospective cohort of 403 patients relating to perioperative morbidity-mortality. Data were collected from a standardized protocol on gender, age, comorbidities, medications used, smoking, alcohol abuse, chronic use of benzodiazepine, nutritional status, presence of anemia, activities of daily living, American Society of Anesthesiology classification, Detsky’s modified cardiac risk index - American College of Physicians, renal function evaluation, pulmonary risk according to the Torrington scale, risk of thromboembolic events, presence of malignant disease and complementary examinations. RESULTS: The mean age of the subjects was 70.8 ± 8.1 years. The “very old” (≥80 years) represented 14%. The mortality rate was 8.2%, and the complication rate was 15.8%. Multiple logistic regression showed that a history of coronary heart disease (OR: 3.75; p=0.02) and/or valvular heart disease (OR: 31.79; p=0.006) were predictors of mortality. The American Society of Anesthesiology classification was shown to be the best scale to mark risk (OR: 3.01; p=0.016). Nutritional status was a protective factor, in which serum albumin increases of 1 mg/dl decreased risk by 63%. DISCUSSION: The results indicate that serum albumin, coronary heart disease, valvular heart disease and the American Society of Anesthesiology classification could be prognostic predictors for aged patients in a perioperative setting. In this sample, provided that pulmonary, cardiac and thromboembolic risks were properly controlled, they did not constitute risk factors for mortality. Furthermore, continuous effort to learn more about the preoperative assessment of elderly patients could yield intervention possibilities and minimize morbimortality. Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2008-04 /pmc/articles/PMC2664206/ /pubmed/18438567 Text en Copyright © 2008 Hospital das Clínicas da FMUSP
spellingShingle Clinical Sciences
Machado, Adriana Nunes
do Carmo Sitta, Maria
Filho, Wilson Jacob
Garcez-Leme, Luíz Eugênio
Prognostic Factors for Mortality Among Patients Above the 6(th) Decade Undergoing Non-Cardiac Surgery: (Cares – Clinical Assessment and Research in Elderly Surgical Patients)
title Prognostic Factors for Mortality Among Patients Above the 6(th) Decade Undergoing Non-Cardiac Surgery: (Cares – Clinical Assessment and Research in Elderly Surgical Patients)
title_full Prognostic Factors for Mortality Among Patients Above the 6(th) Decade Undergoing Non-Cardiac Surgery: (Cares – Clinical Assessment and Research in Elderly Surgical Patients)
title_fullStr Prognostic Factors for Mortality Among Patients Above the 6(th) Decade Undergoing Non-Cardiac Surgery: (Cares – Clinical Assessment and Research in Elderly Surgical Patients)
title_full_unstemmed Prognostic Factors for Mortality Among Patients Above the 6(th) Decade Undergoing Non-Cardiac Surgery: (Cares – Clinical Assessment and Research in Elderly Surgical Patients)
title_short Prognostic Factors for Mortality Among Patients Above the 6(th) Decade Undergoing Non-Cardiac Surgery: (Cares – Clinical Assessment and Research in Elderly Surgical Patients)
title_sort prognostic factors for mortality among patients above the 6(th) decade undergoing non-cardiac surgery: (cares – clinical assessment and research in elderly surgical patients)
topic Clinical Sciences
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664206/
https://www.ncbi.nlm.nih.gov/pubmed/18438567
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