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Difficulties Reported by Hiv-Infected Patients Using Antiretroviral Therapy in Brazil
OBJECTIVE: To describe the degree of difficulty that HIV-infected patients have with therapy treatment. INTRODUCTION: Patients’ perceptions about their treatment are a determinant factor for improved adherence and a better quality of life. METHODS: Two cross-sectional analyses were conducted in publ...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664217/ https://www.ncbi.nlm.nih.gov/pubmed/18438569 |
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author | Guimarães, Mark Drew Crosland Rocha, Gustavo Machado Campos, Lorenza Nogueira de Freitas, Felipe Melo Teixeira Gualberto, Felipe Augusto Souza Teixeira, Ramiro d’Ávila Rivelli de Castilho, Fábio Morato |
author_facet | Guimarães, Mark Drew Crosland Rocha, Gustavo Machado Campos, Lorenza Nogueira de Freitas, Felipe Melo Teixeira Gualberto, Felipe Augusto Souza Teixeira, Ramiro d’Ávila Rivelli de Castilho, Fábio Morato |
author_sort | Guimarães, Mark Drew Crosland |
collection | PubMed |
description | OBJECTIVE: To describe the degree of difficulty that HIV-infected patients have with therapy treatment. INTRODUCTION: Patients’ perceptions about their treatment are a determinant factor for improved adherence and a better quality of life. METHODS: Two cross-sectional analyses were conducted in public AIDS referral centers in Brazil among patients initiating treatment. Patients interviewed at baseline, after one month, and after seven months following the beginning of treatment were asked to classify and justify the degree of difficulty with treatment. Logistic regression was used for analysis. RESULTS: Among 406 patients initiating treatment, 350 (86.2%) and 209 (51.5%) returned for their first and third visits, respectively. Treatment perceptions ranged from medium to very difficult for 51.4% and 37.3% on the first and third visits, respectively. The main difficulties reported were adverse reactions to the medication and scheduling. A separate logistic regression indicated that the HIV-seropositive status disclosure, symptoms of anxiety, absence of psychotherapy, higher CD4+ cell count (> 200/mm(3)) and high (> 4) adverse reaction count reported were independently associated with the degree of difficulty in the first visit, while CDC clinical category A, pill burden (> 7 pills), use of other medications, high (> 4) adverse reaction count reported and low understanding of medical orientation showed independent association for the third visit. CONCLUSIONS: A significant level of difficulty was observed with treatment. Our analyses suggest the need for early assessment of difficulties with treatment, highlighting the importance of modifiable factors that may contribute to better adherence to the treatment protocol. |
format | Text |
id | pubmed-2664217 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo |
record_format | MEDLINE/PubMed |
spelling | pubmed-26642172009-05-13 Difficulties Reported by Hiv-Infected Patients Using Antiretroviral Therapy in Brazil Guimarães, Mark Drew Crosland Rocha, Gustavo Machado Campos, Lorenza Nogueira de Freitas, Felipe Melo Teixeira Gualberto, Felipe Augusto Souza Teixeira, Ramiro d’Ávila Rivelli de Castilho, Fábio Morato Clinics Clinical Sciences OBJECTIVE: To describe the degree of difficulty that HIV-infected patients have with therapy treatment. INTRODUCTION: Patients’ perceptions about their treatment are a determinant factor for improved adherence and a better quality of life. METHODS: Two cross-sectional analyses were conducted in public AIDS referral centers in Brazil among patients initiating treatment. Patients interviewed at baseline, after one month, and after seven months following the beginning of treatment were asked to classify and justify the degree of difficulty with treatment. Logistic regression was used for analysis. RESULTS: Among 406 patients initiating treatment, 350 (86.2%) and 209 (51.5%) returned for their first and third visits, respectively. Treatment perceptions ranged from medium to very difficult for 51.4% and 37.3% on the first and third visits, respectively. The main difficulties reported were adverse reactions to the medication and scheduling. A separate logistic regression indicated that the HIV-seropositive status disclosure, symptoms of anxiety, absence of psychotherapy, higher CD4+ cell count (> 200/mm(3)) and high (> 4) adverse reaction count reported were independently associated with the degree of difficulty in the first visit, while CDC clinical category A, pill burden (> 7 pills), use of other medications, high (> 4) adverse reaction count reported and low understanding of medical orientation showed independent association for the third visit. CONCLUSIONS: A significant level of difficulty was observed with treatment. Our analyses suggest the need for early assessment of difficulties with treatment, highlighting the importance of modifiable factors that may contribute to better adherence to the treatment protocol. Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2008-04 /pmc/articles/PMC2664217/ /pubmed/18438569 Text en Copyright © 2008 Hospital das Clínicas da FMUSP |
spellingShingle | Clinical Sciences Guimarães, Mark Drew Crosland Rocha, Gustavo Machado Campos, Lorenza Nogueira de Freitas, Felipe Melo Teixeira Gualberto, Felipe Augusto Souza Teixeira, Ramiro d’Ávila Rivelli de Castilho, Fábio Morato Difficulties Reported by Hiv-Infected Patients Using Antiretroviral Therapy in Brazil |
title | Difficulties Reported by Hiv-Infected Patients Using Antiretroviral Therapy in Brazil |
title_full | Difficulties Reported by Hiv-Infected Patients Using Antiretroviral Therapy in Brazil |
title_fullStr | Difficulties Reported by Hiv-Infected Patients Using Antiretroviral Therapy in Brazil |
title_full_unstemmed | Difficulties Reported by Hiv-Infected Patients Using Antiretroviral Therapy in Brazil |
title_short | Difficulties Reported by Hiv-Infected Patients Using Antiretroviral Therapy in Brazil |
title_sort | difficulties reported by hiv-infected patients using antiretroviral therapy in brazil |
topic | Clinical Sciences |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664217/ https://www.ncbi.nlm.nih.gov/pubmed/18438569 |
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