Comparison of Different Analytic Algorithms for Interpretation of the Swedish Interactive Threshold Algorithm Strategy

OBJECTIVE: To compare 4 analytic algorithms for interpretation of the Swedish Interactive Threshold Algorithm. INTRODUCTION: Analytic algorithms were initially developed for interpretation of standard automated perimetry (using a full threshold strategy). The Swedish interactive threshold algorithm is a novel strategy that was developed to shorten test duration. METHODS: One hundred forty-three printouts of normal and glaucomatous patients were analyzed using Caprioli’s (strict, moderate and liberal) criteria and Anderson’s modified criteria for perimetric defect. Areas under the receiver operator characteristics (ROC) curves, sensitivity, and specificity for each criteria were calculated. RESULTS: Caprioli’s strict and Anderson’s modified criteria presented similar sensitivity (94.5% and 92.3%, respectively) and specificity (63.5% and 61.5%, respectively). Caprioli’s liberal criteria were more sensitive (98.9%) and less specific (42.5%) than the other three criteria. CONCLUSION: Both Caprioli’s and Anderson’s modified criteria can be used for interpretation of the Swedish interactive threshold algorithm.