Cargando…

Beneficial Effects of Estrogen in a Mouse Model of Cerebrovascular Insufficiency

BACKGROUND: The M(5) muscarinic acetylcholine receptor is known to play a crucial role in mediating acetylcholine dependent dilation of cerebral blood vessels. Previously, we reported that male M(5) muscarinic acetylcholine knockout mice (M5R (−/−) mice) suffer from a constitutive constriction of ce...

Descripción completa

Detalles Bibliográficos
Autores principales: Kitamura, Naohito, Araya, Runa, Kudoh, Moeko, Kishida, Haruo, Kimura, Tetsuya, Murayama, Miyuki, Takashima, Akihiko, Sakamaki, Yuriko, Hashikawa, Tsutomu, Ito, Shingo, Ohtsuki, Sumio, Terasaki, Tetsuya, Wess, Jürgen, Yamada, Masahisa
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664330/
https://www.ncbi.nlm.nih.gov/pubmed/19357782
http://dx.doi.org/10.1371/journal.pone.0005159