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Quantitative exploration of the catalytic landscape separating divergent plant sesquiterpene synthases

Throughout molecular evolution, organisms create assorted chemicals in response to varying ecological niches. Catalytic landscapes underlie metabolic evolution, wherein mutational steps alter the biosynthetic properties of enzymes. We report the first systematic quantitative characterization of a ca...

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Detalles Bibliográficos
Autores principales:	O’Maille, P.E., Malone, A., Dellas, N, Hess, B. A., Smentek, L., Sheehan, I., Greenhagen, B.T., Chappell, J., Manning, G., Noel, J.P.
Formato:	Texto
Lenguaje:	English
Publicado:	2008
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664519/ https://www.ncbi.nlm.nih.gov/pubmed/18776889 http://dx.doi.org/10.1038/nchembio.113

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