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Termination of NF-κB activity through a gammaherpesvirus protein that assembles an EC(5)S ubiquitin-ligase
Host colonisation by lymphotropic gammaherpesviruses depends critically on the expansion of viral genomes in germinal centre (GC) B cells. Yet, host and virus molecular mechanisms involved in driving such proliferation remain largely unknown. Here, we show that the ORF73 protein encoded by the murid...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664658/ https://www.ncbi.nlm.nih.gov/pubmed/19322197 http://dx.doi.org/10.1038/emboj.2009.74 |