Termination of NF-κB activity through a gammaherpesvirus protein that assembles an EC(5)S ubiquitin-ligase

Host colonisation by lymphotropic gammaherpesviruses depends critically on the expansion of viral genomes in germinal centre (GC) B cells. Yet, host and virus molecular mechanisms involved in driving such proliferation remain largely unknown. Here, we show that the ORF73 protein encoded by the murid...

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Detalles Bibliográficos
Autores principales: Rodrigues, Lénia, Filipe, Josina, Seldon, Mark P, Fonseca, Lidia, Anrather, Josef, Soares, Miguel P, Simas, J Pedro
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664658/
https://www.ncbi.nlm.nih.gov/pubmed/19322197
http://dx.doi.org/10.1038/emboj.2009.74

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