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Use of Gene Expression Profiles of Peripheral Blood Lymphocytes to Distinguish BRCA1 Mutation Carriers in High Risk Breast Cancer Families

Mutations in two major genes, BRCA1 and BRCA2, account for up to 30% of families with hereditary breast cancer. Unfortunately, in most families there is little to indicate which gene should be targeted first for mutation screening, which is labor intensive, time consuming and often prohibitively exp...

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Detalles Bibliográficos
Autores principales: Vuillaume, Marie-Laure, Uhrhammer, Nancy, Vidal, Véronique, Vidal, Valérie Sylvain, Chabaud, Valérie, Jesson, Beline, Kwiatkowski, Fabrice, Bignon, Yves-Jean
Formato: Texto
Lenguaje:English
Publicado: Libertas Academica 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664702/
https://www.ncbi.nlm.nih.gov/pubmed/19352458

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