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Inhibition of S6K1 accounts partially for the anti-inflammatory effects of the arginase inhibitor L-norvaline

BACKGROUND: Pharmacological inhibition of endothelial arginase-II has been shown to improve endothelial nitric oxide synthase (eNOS) function and reduce atherogenesis in animal models. We investigated whether the endothelial arginase II is involved in inflammatory responses in endothelial cells. MET...

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Detalles Bibliográficos
Autores principales: Ming, Xiu-Fen, Rajapakse, Angana Gupta, Carvas, João Miguel, Ruffieux, Jean, Yang, Zhihong
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664787/
https://www.ncbi.nlm.nih.gov/pubmed/19284655
http://dx.doi.org/10.1186/1471-2261-9-12

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