Cargando…

Functional and genetic analysis in type 2 diabetes of Liver X receptor alleles – a cohort study

BACKGROUND: Liver X receptor alpha (LXRA) and beta (LXRB) regulate glucose and lipid homeostasis in model systems but their importance in human physiology is poorly understood. This project aimed to determine whether common genetic variations in LXRA and LXRB associate with type 2 diabetes (T2D) and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dahlman, Ingrid, Nilsson, Maria, Gu, Harvest F, Lecoeur, Cecile, Efendic, Suad, Östenson, Claes G, Brismar, Kerstin, Gustafsson, Jan-Åke, Froguel, Philippe, Vaxillaire, Martine, Dahlman-Wright, Karin, Steffensen, Knut R
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664799/ https://www.ncbi.nlm.nih.gov/pubmed/19292929 http://dx.doi.org/10.1186/1471-2350-10-27

Ejemplares similares

Elk1 and SRF transcription factors convey basal transcription and mediate glucose response via their binding sites in the human LXRB gene promoter
por: Nilsson, Maria, et al.
Publicado: (2007)

IGF-binding protein 1 and abdominal obesity in the development of type 2 diabetes in women
por: Lewitt, Moira S, et al.
Publicado: (2010)

Effects of MCF2L2, ADIPOQ and SOX2 genetic polymorphisms on the development of nephropathy in type 1 Diabetes Mellitus
por: Zhang, Dongying, et al.
Publicado: (2010)

Elk1 and SRF transcription factors convey basal transcription and mediate glucose response via their binding sites in the human LXRB gene promoter
por: Nilsson, Maria, et al.
Publicado: (2008)

Impact of estrogen receptor gene polymorphisms and mRNA levels on obesity and lipolysis – a cohort study
por: Nilsson, Maria, et al.
Publicado: (2007)

Evaluation of the association between the common E469K polymorphism in the ICAM-1 gene and diabetic nephropathy among type 1 diabetic patients in GoKinD population
por: Ma, Jun, et al.
Publicado: (2008)

Estrogen Signalling and the Metabolic Syndrome: Targeting the Hepatic Estrogen Receptor Alpha Action
por: Matic, Marko, et al.
Publicado: (2013)

Correction: Estrogen Signalling and the Metabolic Syndrome: Targeting the Hepatic Estrogen Receptor Alpha Action
por: Matic, Marko, et al.
Publicado: (2019)

Estrogen receptor β: an overview and update
por: Zhao, Chunyan, et al.
Publicado: (2008)

Cardiovascular roles of estrogen receptors: insights gained from knockout models
por: Otsuki, Michio, et al.
Publicado: (2003)

Effects of two common polymorphisms in the 3' untranslated regions of estrogen receptor β on mRNA stability and translatability
por: Putnik, Milica, et al.
Publicado: (2009)

Increased DNA methylation of the SLC30A8 gene promoter is associated with type 2 diabetes in a Malay population
por: Seman, Norhashimah Abu, et al.
Publicado: (2015)

Increased DNA methylation levels of the insulin-like growth factor binding protein 1 gene are associated with type 2 diabetes in Swedish men
por: Gu, Tianwei, et al.
Publicado: (2013)

Excessive Islet NO Generation in Type 2 Diabetic GK Rats Coincides with Abnormal Hormone Secretion and Is Counteracted by GLP-1
por: Salehi, Albert, et al.
Publicado: (2008)

Excessive Islet NO Generation in Type 2 Diabetic GK Rats Coincides with Abnormal Hormone Secretion and Is Counteracted by GLP-1
por: Salehi, Albert, et al.
Publicado: (2008)

Correction: Excessive Islet NO Generation in Type 2 Diabetic GK Rats Coincides with Abnormal Hormone Secretion and Is Counteracted by GLP-1
por: Salehi, Albert, et al.
Publicado: (2008)

Correction: Excessive Islet NO Generation in Type 2 Diabetic GK Rats Coincides with Abnormal Hormone Secretion and Is Counteracted by GLP-1
por: Salehi, Albert, et al.
Publicado: (2008)

The epigenetic signature of subcutaneous fat cells is linked to altered expression of genes implicated in lipid metabolism in obese women
por: Arner, Peter, et al.
Publicado: (2015)

Analysis of common PTPN1 gene variants in type 2 diabetes, obesity and associated phenotypes in the French population
por: Cheyssac, Claire, et al.
Publicado: (2006)

Estrogen receptor β2 induces proliferation and invasiveness of triple negative breast cancer cells: association with regulation of PHD3 and HIF-1α
por: Bialesova, Lucia, et al.
Publicado: (2017)

Epigenetic Regulation of PLIN1 in Obese Women and its Relation to Lipolysis
por: Bialesova, Lucia, et al.
Publicado: (2017)

Evaluation of IGFBP-7 DNA methylation changes and serum protein variation in Swedish subjects with and without type 2 diabetes
por: Gu, Harvest F, et al.
Publicado: (2013)

aP2-Cre-Mediated Inactivation of Estrogen Receptor Alpha Causes Hydrometra
por: Antonson, Per, et al.
Publicado: (2014)

The Common FTO Genetic Polymorphism rs9939609 is Associated with Increased BMI in Type 1 Diabetes but not with Diabetic Nephropathy
por: Gu, Harvest F., et al.
Publicado: (2010)

Adiponectin, IGFBP-1 and -2 are independent predictors in forecasting prediabetes and type 2 diabetes
por: Brismar, Kerstin, et al.
Publicado: (2023)

Induction of USP17 by combining BET and HDAC inhibitors in breast cancer cells
por: Borbely, Gabor, et al.
Publicado: (2015)

Association of intercellular adhesion molecule 1 (ICAM1) with diabetes and diabetic nephropathy
por: Gu, Harvest F., et al.
Publicado: (2013)

Epigenetic analyses of the insulin-like growth factor binding protein 1 gene in type 1 diabetes and diabetic nephropathy
por: Gu, Tianwei, et al.
Publicado: (2014)

Comments on Post‐pancreatitis diabetes mellitus is common in chronic pancreatitis and is associated with adverse outcomes: Authors' reply
por: Dugic, Ana, et al.
Publicado: (2023)

Evaluation of Antidiabetic Effects of the Traditional Medicinal Plant Gynostemma pentaphyllum and the Possible Mechanisms of Insulin Release
por: Lokman, Ezarul Faradianna, et al.
Publicado: (2015)

Expression of Protein Kinase C Isoforms in Pancreatic Islets and Liver of Male Goto-Kakizaki Rats, a Model of Type 2 Diabetes
por: Ahmed, Mohammed Seed, et al.
Publicado: (2015)

Correction: Expression of Protein Kinase C Isoforms in Pancreatic Islets and Liver of Male Goto-Kakizaki Rats, a Model of Type 2 Diabetes
por: Seed Ahmed, Mohammed, et al.
Publicado: (2015)

Estrogen receptor beta as a novel target of androgen receptor action in breast cancer cell lines
por: Rizza, Pietro, et al.
Publicado: (2014)

Dataset of bond enthalpies (ε(AA), ε(AB), ε(BB)) in 975 binary intermetallic compounds
por: Miracle, Daniel, et al.
Publicado: (2021)

Glucose-Dependent Regulation of NR2F2 Promoter and Influence of SNP-rs3743462 on Whole Body Insulin Sensitivity
por: Boutant, Marie, et al.
Publicado: (2012)

Ca(2+)–Secretion Coupling Is Impaired in Diabetic Goto Kakizaki rats
por: Rose, Tobias, et al.
Publicado: (2007)

3G evolution: HSPA and LTE for mobile broadband
por: Dahlman, Erik
Publicado: (2007)

3G evolution: HSPA and LTE for mobile broadband
por: Dahlman, Erik
Publicado: (2008)

Estrogen Enhances the Expression of the Polyunsaturated Fatty Acid Elongase Elovl2 via ERα in Breast Cancer Cells
por: González-Bengtsson, Amanda, et al.
Publicado: (2016)

HIF-1 mediated activation of antimicrobial peptide LL-37 in type 2 diabetic patients
por: Mohanty, Soumitra, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_khop9imjjnr8uq4bmel2eqd7mn