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Active State-like Conformational Elements in the β(2)-AR and a Photoactivated Intermediate of Rhodopsin Identified by Dynamic Properties of GPCRs†

[Image: see text] G-Protein-coupled receptors (GPCRs) adopt various functionally relevant conformational states in cell signaling processes. Recently determined crystal structures of rhodopsin and the β(2)-adrenergic receptor (β(2)-AR) offer insight into previously uncharacterized active conformatio...

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Detalles Bibliográficos
Autores principales: Han, Daniel S., Wang, Simon X., Weinstein, Harel
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2008
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664832/
https://www.ncbi.nlm.nih.gov/pubmed/18558776
http://dx.doi.org/10.1021/bi800442g