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Active State-like Conformational Elements in the β(2)-AR and a Photoactivated Intermediate of Rhodopsin Identified by Dynamic Properties of GPCRs†
[Image: see text] G-Protein-coupled receptors (GPCRs) adopt various functionally relevant conformational states in cell signaling processes. Recently determined crystal structures of rhodopsin and the β(2)-adrenergic receptor (β(2)-AR) offer insight into previously uncharacterized active conformatio...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664832/ https://www.ncbi.nlm.nih.gov/pubmed/18558776 http://dx.doi.org/10.1021/bi800442g |