Repression of PKR Mediates Palmitate-Induced Apoptosis in HepG2 Cells through Bcl-2

In the present study we found that double-stranded RNA-dependent protein kinase (PKR) regulates the protein expression level and the phosphorylation of Bcl-2 and exploits an anti-apoptotic role in human hepatocellular carcinoma cells (HepG2). Saturated free fatty acids (FFAs), e.g. palmitate, have b...

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Detalles Bibliográficos
Autores principales: Yang, Xuerui, Chan, Christina
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664847/
https://www.ncbi.nlm.nih.gov/pubmed/19259124
http://dx.doi.org/10.1038/cr.2009.25

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664847/
https://www.ncbi.nlm.nih.gov/pubmed/19259124
http://dx.doi.org/10.1038/cr.2009.25

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