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Repression of PKR Mediates Palmitate-Induced Apoptosis in HepG2 Cells through Bcl-2
In the present study we found that double-stranded RNA-dependent protein kinase (PKR) regulates the protein expression level and the phosphorylation of Bcl-2 and exploits an anti-apoptotic role in human hepatocellular carcinoma cells (HepG2). Saturated free fatty acids (FFAs), e.g. palmitate, have b...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664847/ https://www.ncbi.nlm.nih.gov/pubmed/19259124 http://dx.doi.org/10.1038/cr.2009.25 |